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  • Anti-PTEN Polyclonal Antibody
產(chǎn)品名稱(chēng)：

Anti-PTEN Polyclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價(jià)格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時(shí)間： 2022-08-15
Anti-PTEN Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號(hào)K106537P
規(guī)格50ul /100ul供貨周期現(xiàn)貨
主要用途WB應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁

Anti-PTEN Polyclonal Antibody

英文名稱(chēng)Anti-PTEN Polyclonal Antibody
宿主Rabbit
別名10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;PTENbeta;TEP1
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量47kDa
Gene ID5728
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human PTEN
性狀液體
Public Immunogen RangeA synthetic peptide of human PTEN
Subcellular LocationsCytoplasm Nucleus PML body Secreted
Swiss ProtP60484
克隆類(lèi)型Polyclonal Antibody
背景資料This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

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